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1. A history of the morphology of Alzheimer`s Disease
In 1906 the pathologist/psychiatrist Alois Alzheimer reported to a group of German psychiatrists the story of a 55-year-old woman who died after several years of progressive dementia, and in whose brain he had found both senile plaques and neurofibrillary tangles. Alzheimer had applied newly discovered silver stains to the tissue in order to better delineate these microscopic lesions. Plaques had been previously seen, presumably with aniline stains, but not in association with dementia, while cortical tangles had not been prev...

2. The clinical diagnosis of Alzheimer`s Disease
Retrospective studies in the 1970s showed that there was often a 30 to 50% error rate simply in deciding whether a patient did or did not have dementia, let alone what kind of dementia the patient might have. For example, in an institution as sophisticated as the Maudsley Hospital, the major psychiatric hospital in Great Britain, it had been found that the diagnosis of the presenile form of Alzheimer’s disease was in error by 30%, most of the patients misdiagnosed as having been depressed. LEARNING TO DIFFERENTI...

3. Alzheimer`s Disease ~ Who is at risk
Although aging per se causes neither dementia nor Alzheimer’s disease, it is the most strongly associated risk factor for AD. Family history, or genetic predisposition, is another important risk factor; a history of AD in a first-degree relative (parent or sibling) increases the odds of developing AD three- to fourfold. A history of severe head injury that leads to brief loss of consciousness doubles the risk of developing AD. These three risk factors — age, genetic predisposition, and head trauma — meet the accepted...

4. Neurobiological basis of Alzheimer`s Disease
Although Alzheimer's disease is a distinct disease defined by its characteristic clinical course and pathology, it is a heterogeneous condition with varied manifestations. The rate of cognitive impairment, for example, differs markedly among individuals. The characteristic features of Alzheimer's disease brain pathology also differ sharply among people. Though the onset, course, and sequence of events may vary widely, it seems likely nonetheless that the destructive forces involved ultimately converge to cause nerve cell (neur...

5. THE BIGGEST HAZARDS OF RETIREMENT PLANNING
Setting goals is easy; following through on them is more difficult. Many times, I’ve found that people set their sights too high, only to see themselves fall short of their goals. It’s not because they failed, entirely, to reach these goals; it’s because they didn’t break down their goals, and became overwhelmed. Smaller hills are easier to climb than very tall mountains. Therefore, break down your large mountainous dream into smaller, more attainable foothills. By doing this, you’ll be more apt to follow...

6. THE HISTORY OF RETIREMENT
The notion of retirement really didn’t have a big impact on America until after World War II. At that point, people would give 30 to 40 years of their lives to one company, who in return, would pay workers good salaries and generous pensions once they stopped working. In that way, companies were very paternalistic toward their employees. The employees were also very dedicated to their employers. Working until you were 65, quitting, and then enjoying your pension income was the common thing to do. People looked forward to the tim...

7. ESTIMATING YOUR RETIREMENT NEEDS
Once you have set your goals and you have started to form a clear picture of what you would like to do during your retirement, you need to figure out how much money you will need to live on. If only that was all there was! Unfortunately, our economy isn’t static, and will be subject to many fluctuations between now and when you begin your retirement. That means that not only do we not know how the stock markets will perform, but we also don’t know what kind of inflation we will face over the next few years. It could be tha...

8. With the Leg Wedge Pillow the pain in your back will not be back
Do you or someone you know suffer from constant back pain? According to back pain statistics, back pain is one of the most common discomforts than Americans have, and also one of the main reasons for which they can not sleep properly or live a normal life. Back pain may have several causes like having an accident, lifting heavy objects and many others. But one of the most usual causes is a bad posture. A good posture is very important to get back pain relief and we’ll explain why. The three natural curves and the discs of the...