You should feel no discomfort during an enema; if you experience pain or cramping, go sit on the toilet right away.

If you're having an enema in preparation for anal sex, you should do it at least two to three hours prior to having sex to give your body a chance to reabsorb water and recover.

Storebought enemas like the Fleet Ready-to-Use Enema' contain laxatives and harsh chemicals that can irritate your rectum; plain filtered water without additives is a better idea. Never use a vaginal douche in your rectum.

Do not use a turkey baster to give yourself or your partner an enema. Turkey basters are too long and are made of plastic that is inflexible and may have rough seams.

Depending on the state of your water supply, you may want to use heated bottled water (100°F).

I've heard about vodka enemas, coffee enemas, and other exotic enemas, but these are really not good for you. Any liquid you put in your rectum gets absorbed so quickly that it's like shooting it in your veins. It will ultimately irritate your rectum, and it could make you very, very sick.

Allow yourself plenty of time and several bowel movements before you're cleaned out.

Do not share enema equipment.

Clean and disinfect your enema equipment carefully (diluted liquid bleach is a good disinfectant).

Carefully read and follow all instructions that accompany enema kits or equipment.

It's not a good idea to have enemas too frequently. They tend to stress out your rectum, and too much of this evacuation can throw your rectum, bowels, and gastrointestinal tract off balance. According to sex educator Robert Morgan, frequent use of enemas can wash away mucosa from your rectum and cause colitis/proctitis.

If, after an enema, you don't have a bowel movement or expel any liquid, you could be dehydrated or have a serious condition. See a doctor immediately.